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Anti-PR3 (cANCA)
Anti-PR3 hs
ORG 518, ORG 218
ORG 618, ORG 318
The Anti-PR3 ELISA by ORGENTEC is an indi- rect enzyme immunoassay for the quantitative serological detection of autoantibodies against proteinase 3 (PR3), a lysosomal enzyme of neutrophil granulocytes and monocytes. The Anti-PR3 assay is an important element in the diagnosis of Wegener’s granulomatosis.
Autoantibodies against PR3 play a critical role in the diagnosis of this life-threatening disease. At present, a combination of indirect immunofluo- rescence (IFT) and an antigenspecific ELISA is currently recommended for the detection of these antibodies.
The Anti-PR3 hs now represents an innovative ELISA whose unusually high sensitivity of 96 % and simultaneously high specificity of 99 % pro- vide outstanding diagnostic significance in ANCA diagnosis. In addition, the results of the Anti-PR3 hs correlate very well with those of indirect immunofluorescence.
Tests
12 x 8 determinations
12 or 24 Alegria® test strips
Instruction for Use: ORG 518-0802-02-gb.pdf
Material-Safety-Datasheet: ORG 518-msds-v3.pdf
ORGENTEC Literature Service: ORG Literature Service_ANCA_Vasculitis.pdf