| Celiac disease is defined as a gluten sensitive enteropathy.
It is caused by a hypersensitivity reaction in
response to gliadin, a protein being present in many
cereals. This, non IgE mediated food allergy leads to
massive malabsorption disturbances and is characterized
by a complete atrophy of the villi and a hyperplasia
of the crypts of the upper intestine. The highly
specific and sensitive serological determination of IgA
and IgG antibodies against gliadin is a useful tool in
diagnosting celiac disease. Gliadin antibodies titre correlate
very well with the morphological appearance of
the mucosa of the upper intestine. Thus the serological
test represents a reliable method to diagnose celiac
disease and to monitor patients for their adherence to
the glutenfree diet. |
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| Tests |
12 x 8 Tests |
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| Calculation |
quantitative |
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| Range |
0 – 100 U/ml |
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| Cut-off |
12 U/ml
Screen: 15 U/ml |
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| Sensitivity |
0.5 U/ml |
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| Calibration |
arbitrary |
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| Substrate |
TMB / 450 nm |
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Instruction for Use: ORG 534A-0508-01-gb.pdf
Material-Safety-Datasheet: ORG 534A.pdf