Anti-PR3 hs

Anti-PR3 hs is an ELISA test for the quantitative determination of IgG antibodies against proteinase 3 (PR3) in human serum or plasma.

The Anti-PR3 assay is an important element in the diagnosis of granulomatosis with polyangiitis (Wegener’s granulomatosis). Autoantibodies directed against PR3 play a critical role in the diagnosis of this life-threatening disease. A combination of indirect immunofluorescence (IIF) and an antigen-specific ELISA is currently recommended for the detection of these autoantibodies.

Based on a special coating technology, Anti-PR3 hs (high sensitive) (ORG 618, ORG 318) now represents an innovative ELISA whose extraordinarily high sensitivity of 96 % and specificity of 99 % provide outstanding diagnostic significance in ANCA serology. In addition, the results of Anti-PR3 hs (high sensitive) correlate well with those of IIF.

Specifications

Product Number ORG 618
Tests12 x 8 tests
Calibrationinternal
Calculationquantitative
Range0 - 200 U/ml
Cut-off10 U/ml
Coating proteinase 3 (PR3)
Alegria

ORG 318   ORG 389  

ELISA

ORG 530   ORG 689  

BLOT

ORG 789  

Documentation

Instruction for Use
Safety Data Sheet