Anti-Tissue-Transglutaminase

The Anti- Tissue-Transglutaminase ELISA tests from ORGENTEC are used for automated quantitative determination of IgA and/or IgG antibodies against Tissue-Transglutaminase (tTG) in human serum or plasma. The assays Anti-Tissue-Transglutaminase IgA, Anti-Tissue-Transglutaminase IgG, and Anti-Tissue-Transglutaminase Screen support a diagnosis of celiac disease. Celiac disease (sprue) is one of the most common food-induced diseases. It manifests itself as hypersensitivity to gluten in food, which is found in wheat, rye, and barley. tTG belongs to a family of calcium-dependent enzymes that catalyze the transfer of protein-bound glutamine residues to primary amines. The enzyme is released by inflamed cells and is the primary antigen for autoantibodies of celiac disease patients. The Anti-Tissue-Transglutaminase assay provides a simple, non-invasive alternative to conventional immunofluorescence. Its high reliability, sensitivity, and specificity make it an ideal tool for screening patients with clinical symptoms. The Anti-tTG test by ORGENTEC is available both for screening by simultaneous detection of IgG and IgA or as single tests for individual analysis of IgA or IgG antibodies.

Anti-Tissue-Transglutaminase IgA

Anti-Tissue-Transglutaminase IgA is an ELISA test for the quantitative determination of IgA antibodies against tissue transglutaminase (tTG) in human serum or plasma.

Specifications

Product Number ORG 540A
Tests12 x 8 tests
Calibrationinternal
Calculationquantitative
Range0 - 200 U/ml
Cut-off10 U/ml
Coating tissue transglutaminase (tTG) (human recombinant)
Alegria

ORG 240A   ORG 240G   ORG 240S  

BLOT

ORG 740  

Documentation

Instruction for Use
Safety Data Sheet

Anti-Tissue-Transglutaminase IgG

Anti-Tissue-Transglutaminase IgG is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against tissue transglutaminase (tTG) in human serum or plasma.

Specifications

Product Number ORG 540G
Tests12 x 8 tests
Calibrationinternal
Calculationquantitative
Range0 - 200 U/ml
Cut-off 10 U/ml
Coating tissue transglutaminase (tTG) (human recombinant)
Alegria

ORG 240A   ORG 240G   ORG 240S  

BLOT

ORG 740  

Documentation

Instruction for Use
Safety Data Sheet

Anti-Tissue-Transglutaminase Screen

Anti-Tissue-Transglutaminase Screen is an ELISA test for the quantitative determination of IgG and IgA antibodies against tissue transglutaminase (tTG) in human serum or plasma.

Specifications

Product Number ORG 540S
Tests12 x 8 tests
Calibrationinternal
Calculationquantitative
Range0 - 200 U/ml
Cut-off 15 U/ml
Coating tissue transglutaminase (tTG) (human recombinant)
Alegria

ORG 240A   ORG 240G   ORG 240S  

BLOT

ORG 740  

Documentation

Instruction for Use
Safety Data Sheet