Anti-ssDNA

Anti-ssDNA is an ELISA test system for the quantitative, in-vitro determination of IgG antibodies against single-stranded DNA in human serum or plasma.

This assay is used for the serological detection of systemic lupus erythematosus (SLE) and drug-induced lupus. The antibody titers correlate with disease activity: In the serum of SLE patients, ssDNA antibodies are found in up to 87 % of patients during acute relapses of the disease but only 43 % of patients during inactive phases. In conjunction with the detection of histone antibodies, the determination of ssDNA antibodies is helpful for the differential diagnosis of drug-induced lupus. ssDNA antibodies are found in over 50 % of these patients. Antibodies against ssDNA are additionally found in patients with collagenoses and juvenile chronic arthritis (JCA).

Specifications

Product Number ORG 605
Tests12 x 8 tests
Calibrationinternal
Calculationquantitative
Range0 - 200 U/ml
Cut-off 20 U/ml
Coating ssDNA (recombinant)
Alegria

ORG 200   ORG 205  

ELISA

ORG 600  

Documentation

Instruction for Use
Safety Data Sheet