Anti-beta-2-Glycoprotein I

The assay contributes to the diagnosis of antiphospholipid syndrome (APS). The clinical symptoms of APS alone are not sufficiently specific to make a definitive diagnosis. Laboratory tests thus play an important role in the diagnosis of the disease. In patients with APS, autoantibodies are formed that bind to phospholipids like cardiolipin or to phospholipid-binding proteins like beta-2-glycoprotein. Detection of these autoantibodies is an integral part of the classification criteria issued by the International Society on Thrombosis and Hemostasis. Beta-2-GPI antibodies are associated with the occurrence of arterial or venous thrombosis, as well as with recurring miscarriage. Beta-2-GPI antibodies are considered to have a higher specificity than cardiolipin antibodies for the detection of APS; they can be detected even when the cardiolipin test result is negative.

Anti-beta-2-Glycoprotein I IgG/IgM

Anti-beta-2-Glycoprotein I IgG/IgM is an ELISA test for the quantitative determination of IgG and IgM antibodies against beta-2-glycoprotein I in human serum or plasma.

Specifications

Product Number ORG 521
Tests12 x 8 tests
CalibrationHarris sera, IRP 97/656 (IgG), HCAL (IgG) / EY2C9 (IgM)
Calculationquantitative
Range 0 - 100 U/ml
Cut-off8 U/ml
Coating beta-2-glycoprotein I (beta-2-GPI)
Alegria

ORG 221A   ORG 221G   ORG 221M   ORG 221S  

ELISA

ORG 555  

Documentation

Instruction for Use
Safety Data Sheet

Anti-beta-2-Glycoprotein I IgA

Anti-beta-2-Glycoprotein I IgA is an ELISA test for the quantitative determination of IgA antibodies against beta-2-glycoprotein I in human serum or plasma.

Specifications

Product Number ORG 521A
Tests12 x 8 tests
CalibrationHarris sera, IRP 97/656 (IgG), HCAL (IgG) / EY2C9 (IgM)
Calculationquantitative
Range0 - 100 U/ml
Cut-off 8 U/ml
Coating beta-2-glycoprotein I (beta-2-GPI)
Alegria

ORG 221A   ORG 221G   ORG 221M   ORG 221S  

ELISA

ORG 555  

Documentation

Instruction for Use
Safety Data Sheet

Anti-beta-2-Glycoprotein I Screen

Anti-beta-2-Glycoprotein I Screen is an ELISA- test for the quantitative determination of antibodies against beta-2-glycoprotein I in human serum or plasma. This test simultaneously tests for IgA, IgM, and IgG antibodies

Specifications

Product Number ORG 521S
Tests12 x 8 tests
CalibrationHarris sera, IRP 97/656 (IgG), HCAL (IgG) / EY2C9 (IgM)
Calculationquantitative
Range0 - 90 U/ml
Cut-off10 U/ml
Coating beta-2-glycoprotein I (beta-2-GPI)
Alegria

ORG 221A   ORG 221G   ORG 221M   ORG 221S  

ELISA

ORG 555  

Documentation

Instruction for Use
Safety Data Sheet