Myositis plus

Myositis plus is a membrane-based enzyme immunoassay for the semi-quantitative determination of IgG autoantibodies in human serum or plasma. This immunoblot test is used in cases of suspected polymyositis/dermatomyositis or overlap syndromes as well as for the differential diagnosis of scleroderma.
Autoantibodies against nuclear (ANA) and/or cytoplasmic antigens are found in nearly 90 % of patients with poly- or dermatomyositis. The Myositis plus test detects myositis-specific autoantibodies (MSA) that are generally only found in cases of idiopathic inflammatory myopathy and thus act as markers for this condition. In addition, this test detects myositis-associated autoantibodies (MAA), which are detected in patients with other diseases as well as those with myopathy.
The nine antigens in the Myositis plus test are deposited in bands onto nitrocellulose strips. The test detects autoantibodies characteristic of autoimmune myositis, scleroderma, and overlap syndromes in a single and simple step.

Automated evaluation of immunoblots with iVISION Scanware

iVISION Scanware makes it possible to automate the evaluation of immunoblots. This software allows for the objective assessment of laboratory results and efficiently stores and archives the data.

Specifications

Product Number ORG 760
Tests8 strips / ORG 760-08, 16 strips / ORG 760-16
Calibrationinternal
Calculationsemi-quantitative
Coating histidyl-tRNA synthetase (Jo-1), Ku (p70/80), M2 proteins (PDC-E2, BCOADC-E2, OGDC-E2), Mi-2, PL-12, PL-7, Pm-Scl-100, ribosomal P protein (Rib-P), SRP
Alegria

ORG 200   ORG 206   ORG 213   ORG 238   ORG 216   ORG 217  

ELISA

ORG 506   ORG 513   ORG 514   ORG 538   ORG 539   ORG 546   ORG 600   ORG 516   ORG 517  

BLOT

ORG 710   ORG 711   ORG 722  

Documentation

Instruction for Use
Safety Data Sheet