Anti-Parietal Cell

Anti-Parietal Cell is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against the H+/K+-ATPase of parietal cells in human serum or plasma.

This enzyme transports hydrogen ions into the stomach lumen, regulating the acidic pH value. ELISA test systems for parietal cell antigen are distinguished by their high sensitivity and specificity. Circulating autoantibodies against H+/K+-ATPase are found in 80 to 90 % of patients with pernicious anaemia; however, they are also detected in 2 to 5 % of healthy individuals. In general, parietal cell autoantibodies are found more frequently in older people than in younger ones.

Specifications

Product Number ORG 231
Tests24 Alegria® strips
Calibrationinternal
Calculationquantitative
Range0 - 100 U/ml
Cut-off10 U/ml
Coating H+/K+-ATPase from parietal cells
ELISA

ORG 531  

BLOT

ORG 740  

Documentation

Instruction for Use
Safety Data Sheet