Anti-ssDNA

Anti-ssDNA is an ELISA-based, automated, in-vitro test system for the quantitative, in-vitro determination of IgG antibodies against single-stranded DNA in human serum or plasma.

This assay is used for the serological detection of systemic lupus erythematosus (SLE) and drug-induced lupus. The antibody titers correlate with disease activity: In the serum of SLE patients, ssDNA antibodies are found in up to 87 % of patients during acute relapses of the disease but only 43 % of patients during inactive phases. In conjunction with the detection of histone antibodies, the determination of ssDNA antibodies is helpful for the differential diagnosis of drug-induced lupus. ssDNA antibodies are found in over 50 % of these patients. Antibodies against ssDNA are additionally found in patients with collagenoses and juvenile chronic arthritis (JCA).

Specifications

Product Number ORG 205
Tests24 Alegria® strips
Calibrationinternal
Calculationquantitative
Range0 - 200 U/ml
Cut-off20 U/ml
Coating ssDNA
Alegria

ORG 200  

ELISA

ORG 600   ORG 605  

Documentation

Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 4. Earlier versions and additional languages can be found in the document archive.

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