Anti-Histone is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against histone proteins in human serum or plasma.

Up to 80 % of patients suffering from systemic lupus erythematosus (SLE) and nearly 95 % of patients with drug-induced lupus (DIL) have autoantibodies against histone proteins in their antibody profile. Histone antibodies are not specific to a particular disease. Aside from SLE and DIL, they also occur in patients with numerous other rheumatic diseases, including rheumatoid arthritis, juvenile chronic arthritis, and scleroderma.


Product Number ORG 207
Tests24 Alegria® strips
CalibrationWHO MRC 66/233
Range0 - 200 U/ml
Cut-off40 U/ml
Coating histone proteins H1, H2A, H2B, H3, H4

ORG 200  


ORG 507   ORG 600  


Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 4. Earlier versions and additional languages can be found in the document archive.