Anti-SS-A

Anti-SS-A is an ELISA-based, automated, in-vitro, test system for the quantitative determination of IgG antibodies against SS-A 60 and SS-A 52 in human serum or plasma.

This test is useful for the differential diagnosis and monitoring of systemic rheumatic inflammatory autoimmune diseases. SS-A 52 and SS-A 60 are proteins that bind to smaller RNAs and ribonucleoprotein particles in the cell nucleus and cytoplasm. They are thus a component of the human cytoplasmic ribonucleoprotein complex and are extractable nuclear antigens (ENA). Autoantibodies against the two antigens SS-A 52 and SS-A 60 are predominantly found in cases of collagenosis, particularly Sjögren’s syndrome, and various forms of lupus erythematosus.

Specifications

Product Number ORG 208
Tests24 Alegria® strips
Calculationquantitative
Range0 - 200 U/ml
Cut-off 25 U/ml
Coating SS-A 52 (Ro 52), SS-A 60 (Ro 60)
Alegria

ORG 200   ORG 206   ORG 238   ORG 252   ORG 260  

ELISA

ORG 506   ORG 508   ORG 514   ORG 538   ORG 539   ORG 544   ORG 546   ORG 600   ORG 652   ORG 660  

BLOT

ORG 710   ORG 711  

Documentation

Instruction for Use
Safety Data Sheet