ANAscreen

ANAscreen is an ELISA based test system for the qualitative measurement of IgG antibodies against nuclear antigens, SS-A 52, SS-A 60, SS-B, RNP-70, Sm, RNP/Sm, Scl-70, Centromere B, and Jo-1, in human serum or plasma samples.

Antinuclear antibodies (ANA) are detected in patients with systemic autoimmune diseases such as systemic lupus erythematosus (SLE), Sjögren’s syndrome, Sharp syndrome, polymyositis/dermatomyositis, and progressive systemic scleroderma (PSS) with CREST syndrome. ANA thus partially act as makers for the individual connective tissue diseases. Each individual well of the ANAscreen test is coated with a mixture of nine human recombinant and native, highly purified antigens, allowing for sensitive detection of these autoantibodies. After a positive result with this test, further differentiation of the autoantibodies should be carried out with the ANAcombi test or the respective single antigen ELISA assays from ORGENTEC.

Specifications

Product Number ORG 238
Tests24 Alegria® strips
Calculationqualitative
Cut-offIndex > 1.2
Coating centromere B, histidyl-tRNA synthetase (Jo-1), RNP-70, RNP/Sm complex, Scl-70 protein (DNA topoisomerase I), Sm ribonucleoproteins, SS-A 52 (Ro 52), SS-A 60 (Ro 60), SS-B (La)
Alegria

ORG 200   ORG 233   ORG 206   ORG 213   ORG 232   ORG 211   ORG 212   ORG 210   ORG 208   ORG 252   ORG 260   ORG 209  

ELISA

ORG 538   ORG 539   ORG 600   ORG 633   ORG 506   ORG 513   ORG 514   ORG 546   ORG 632   ORG 511   ORG 544   ORG 512   ORG 510   ORG 508   ORG 652   ORG 660   ORG 509  

BLOT

ORG 710   ORG 711   ORG 760  

Documentation

Instruction for Use
Safety Data Sheet