Anti-CCP hs (high sensitive)®

Anti-CCP hs (high sensitive)® is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against cyclic citrullinated peptides (CCP) in human serum or plasma.

Anti-CCP hs (high sensitive)® is based on selected and optimized peptide epitopes from the body’s own MCV protein (modified citrullinated vimentin). Due to its tailored antigen profile, this ELISA attains the highest sensitivity while maintaining high specificity. It is thus positioned as a powerful serological test for the rapid and precise routine diagnosis of rheumatoid arthritis (RA), as well as for the diagnosis of early RA. In conjunction with rheumatoid factor, autoantibodies against citrullinated antigens (ACPA) have been included as determinate factors in the current ACR criteria for the classification of rheumatoid arthritis. Anti-CCP hs (high sensitive)® is an ACPA test that allows for the diagnosis of RA with comparable sensitivity and significantly higher specificity and prognostic power than conventional rheumatoid factor tests.

Specifications

Product Number ORG 301
Tests24 Alegria® strips
Calibrationinternal
Calculationquantitative
Range0 - 1000 U/ml
Cut-off20 U/ml
Coating cyclic citrullinated vimentin peptides (CCP)
ELISA

ORG 601  

Documentation

Instruction for Use
Safety Data Sheet