Anti-VZV IgG Liquor

Alegria® Anti-VZV IgG Liquor is an ELISA-based, automated, in-vitro test system for the comparative quantitative determination of IgG antibodies against varicella zoster virus (VZV) in human serum or plasma. It is used for the detection of IgG antibody synthesis in the central nervous system.

An elevated varicella zoster virus (VZV) antibody index characterizes varizella zoster ganglionitis, often accompanied by facial paralysis. VZV-antibody detection is important for the differential diagnosis of neuroborreliosis. CSF analysis currently is the method of choice to distinguish these infections that may both be the cause of facial paralysis.

In chronic diseases with CNS involvement, e.g. multiple sclerosis (MS) or Lupus with neurological manifestations, an elevated antibody index of anti-measles virus, anti-rubella virus and/or anti-varicella zoster virus can be detected in the CSF. This MRZ reaction is the most sensitive biochemical method for the detection of the pathological immune process in the CNS when the first clinical symptoms of MS appear. In about 90% of MS patients, an increased antibody index against the MRZ combination can be detected.

Specifications

Product Number ORG 914GL
Tests24 Alegria® Test Strips
Calibrationinternal
Calculationquantitative
Range10-200 U/ml
Coating VZV glycoproteins
Alegria

ORG 914A   ORG 914G  

Documentation

Instruction for Use
Safety Data Sheet
Product Information