Anti-Yersinia

Yersinia are often only detectable in stool samples for a short time, and cannot be detected at all in joints affected by reactive arthritis. For these reasons, the serological detection of Yersinia-specific antibodies is important. The ORGENTEC tests for Alegria® detect IgA and IgG antibodies against characteristic Yop proteins (Yersinia outer membrane proteins). The Yop proteins are plasmid-encoded virulence factors and are highly specific for all of the Yersinia species that are pathogenic to humans. After initial exposure to the pathogen, IgM antibodies are formed first, soon followed by the IgG and IgA antibodies. IgM antibodies usually disappear after a few weeks. High IgA and IgG antibody titres are indicative of infection in the recent past. IgG antibodies may persist at low levels for years.

Anti-Yersinia IgA

Alegria® Anti-Yersinia IgA is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgA antibodies against Yersinia sp. In human serum or plasma. Yersinia are Gram negative bacteria found throughout the world in animal reservoirs. Yersinia pestis, which causes bubonic plague, plays a minor role today; however, infections with Yersinia enterocolitica and Yersinia pseudotuberculosis are quite common.

Specifications

Product Number ORG 913A
Tests24 Alegria® strips
Calibrationinternal
Calculationquantitative
Range0 - 200 U/ml
Cut-off25 U/ml
Coating YopD (recombinant)

Documentation

Instruction for Use
Safety Data Sheet
Product Information

Anti-Yersinia IgG

Alegria® Anti-Yersinia IgG is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against Yersinia sp. In human serum or plasma. Yersinia are Gram negative bacteria found throughout the world in animal reservoirs. Yersinia pestis, which causes bubonic plague, plays a minor role today; however, infections with Yersinia enterocolitica and Yersinia pseudotuberculosis are quite common.

Specifications

Product Number ORG 913G
Tests24 Alegria® strips
Calibrationinternal
Calculationquantitative
Range0 - 200 U/ml
Cut-off25 U/ml
Coating YopD (recombinant)

Documentation

Instruction for Use
Safety Data Sheet
Product Information