Anti-EBV (EBNA-1) IgG

Anti-EBV (EBNA-1) IgG is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1) in human serum or plasma.

Epstein-Barr virus (EBV) is the cause of infectious mononucleosis (glandular fever, kissing disease). The pathogen first infects the salivary glands, which leads to general flu-like symptoms. About six to eight weeks after onset of symptoms, patients form IgG antibodies against EBNA-1. The presence of these antibodies indicates transition from the active to the latent phase of the disease. Therefore, detection of IgG antibodies against EBNA-1 allows for exclusion of primary EBV infection Acute EBV infections lead to the unspecific stimulation of the immune system, which can effect false positive results in tests for other antibodies. For differential diagnosis when symptoms are unclear, it is thus always necessary to determine the patient’s EBV status.

Specifications

Product Number ORG 902
Tests24 Alegria® strips
Calibrationinternal
Calculationquantitative
Range0 - 800 U/ml
Cut-off25 U/ml
Coating EBV nuclear antigen (EBNA-1) (recombinant)

Documentation

Instruction for Use
Safety Data Sheet