beta-2-Microglobulin

Beta-2-Microglobulin is an ELISA test for the quantitative determination of beta-2-microglobulin in human serum, plasma, or urine.
Beta-2-microglobulin, the light chain of the major histocompatibility complex class I (HLA 1, MHC I) serves as a tumour marker in cases of multiple myeloma, Hodgkin’s disease, chronic lymphatic leukaemia, and other non-Hodgkin’s lymphomas. Other diseases (infections, autoimmune diseases) that involve activation of the cellular immune system also cause increased beta-2-microglobulin concentrations in serum.
Beta-2-microglobulin is also used as a marker for evaluating the glomerular filtration rate, for the diagnosis and monitoring of tubulointersticial kidney damage, for monitoring kidney function after a kidney transplant, and monitoring HIV infections.
The wells of the microplate are coated with highly specific antibodies against human beta-2-microglobulin.

Specifications

Product Number ORG 5BM
Tests12 x 8 tests
CalibrationWHO B2M
Calculationquantitative
Range0 - 12 µg/ml
Cut-off3 µg/ml Serum /
Coating anti-beta-2-microglobulin antibodies (polyclonal, rabbit)

Documentation

Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 3. Earlier versions and additional languages can be found in the document archive.
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