Anti-Rib-P

Anti-Rib-P is an ELISA test for the quantitative determination of IgG antibodies against ribosomal P proteins (Rib-P, a common epitope of phosphoproteins of the 60S subunit of the ribosomal complex) in human serum or plasma.

Like anti-nuclear antibodies (ANA), anti-cytoplasmic antibodies play a role in rheumatic disease. Of these, the anti-ribosomal antibodies (ARA) are the best characterized. Autoantibodies against ribosomal P-proteins are highly specific markers for diagnostics of systemic lupus erythematosus, because they rarely occur in other autoimmune diseases. ARA are found in only about 10 % of randomly selected SLE patients, but are detected in up to 40 % of SLE patients whose disease status is active. Anti-Rib-P detection is recommended in cases of suspected SLE when antibodies against Sm antigens and double-stranded DNA are absent. Use of the Anti-Rib-P ELISA from ORGENTEC is also indicated when lupus-induced psychosis is suspected.

Specifications

Product Number ORG 517
Tests12 x 8 tests
Calibrationinternal
Calculationquantitative
Range0 - 200 U/ml
Cut-off 10 U/ml
Coating ribosomal P protein (Rib-P)
Alegria

ORG 217  

BLOT

ORG 710   ORG 760  

Documentation

Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 3. Earlier versions and additional languages can be found in the document archive.
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