Anti-ssDNA

Anti-ssDNA is an ELISA test system for the quantitative, in-vitro determination of IgG antibodies against single-stranded DNA in human serum or plasma.

This assay is used for the serological detection of systemic lupus erythematosus (SLE) and drug-induced lupus. The antibody titers correlate with disease activity: In the serum of SLE patients, ssDNA antibodies are found in up to 87 % of patients during acute relapses of the disease but only 43 % of patients during inactive phases. In conjunction with the detection of histone antibodies, the determination of ssDNA antibodies is helpful for the differential diagnosis of drug-induced lupus. ssDNA antibodies are found in over 50 % of these patients. Antibodies against ssDNA are additionally found in patients with collagenoses and juvenile chronic arthritis (JCA).

Specifications

Product Number ORG 605
Tests12 x 8 tests
Calibrationinternal
Calculationquantitative
Range0 - 200 U/ml
Cut-off 20 U/ml
Coating ssDNA (recombinant)
Alegria

ORG 200   ORG 205  

ELISA

ORG 600  

Documentation

Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 3. Earlier versions and additional languages can be found in the document archive.
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