ENA-6-Profile is an ELISA test system for the qualitative determination of IgG antibodies against six extractable nuclear antigens (ENA), SS-A (Ro 52, Ro 60), SS-B, Sm, RNP/Sm, Scl-70 and Jo-1 in human serum or plasma. The test aids to the diagnosis of inflammatory rheumatic connective tissue diseases.
Antibodies against ENA are typically found in patients with lupus erythematosus (SLE), Sjoegren’s syndrome, Sharp syndrome, polymyositis/dermatomyositis, and progressive systemic scleroderma (PSS). Some of these antibodies serve as markers for individual connective tissue diseases. Individual detection of these antibodies with the ENA-6-Profile test thus makes it possible to differentiate these diseases.
The ENA-6-Profile test is based on a modular principle: Each kit contains two color-coded strips for each antigen. Each strip has eight wells coated with an individual highly purified antigen target.


Product Number ORG 546
Tests12 x 8 tests
CalibrationCDC sera
Cut-offIndex > 1.2
Coating histidyl-tRNA synthetase (Jo-1), RNP/Sm complex, Scl-70 protein (DNA topoisomerase I), Smith antigen (Sm), SS-A 52 (Ro 52), SS-A 60 (Ro 60), SS-B (La)

ORG 200   ORG 206   ORG 213   ORG 238   ORG 211   ORG 212   ORG 208   ORG 252   ORG 260   ORG 209  


ORG 506   ORG 513   ORG 514   ORG 538   ORG 539   ORG 600   ORG 511   ORG 544   ORG 512   ORG 508   ORG 652   ORG 660   ORG 509  


ORG 710   ORG 711   ORG 760  


Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 4. Earlier versions and additional languages can be found in the document archive.

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