Anti-Tissue-Transglutaminase

The Anti- Tissue-Transglutaminase ELISA tests from ORGENTEC are used for automated quantitative determination of IgA and/or IgG antibodies against Tissue-Transglutaminase (tTG) in human serum or plasma. The assays Anti-Tissue-Transglutaminase IgA, Anti-Tissue-Transglutaminase IgG, and Anti-Tissue-Transglutaminase Screen support a diagnosis of celiac disease. Celiac disease (sprue) is one of the most common food-induced diseases. It manifests itself as hypersensitivity to gluten in food, which is found in wheat, rye, and barley. tTG belongs to a family of calcium-dependent enzymes that catalyze the transfer of protein-bound glutamine residues to primary amines. The enzyme is released by inflamed cells and is the primary antigen for autoantibodies of celiac disease patients. The Anti-Tissue-Transglutaminase assay provides a simple, non-invasive alternative to conventional immunofluorescence. Its high reliability, sensitivity, and specificity make it an ideal tool for screening patients with clinical symptoms. The Anti-tTG test by ORGENTEC is available both for screening by simultaneous detection of IgG and IgA or as single tests for individual analysis of IgA or IgG antibodies.

Anti-Tissue-Transglutaminase IgA

Anti-Tissue-Transglutaminase IgA is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgA antibodies against tissue transglutaminase (tTG) in human serum or plasma.

Specifications

Product Number ORG 240A
Tests24 Alegria® strips
Calibrationinternal
Calculationquantitative
Range0 - 200 U/ml
Cut-off 10 U/ml
Coating tissue transglutaminase (tTG) (human recombinant)
ELISA

ORG 540A   ORG 540G   ORG 540S  

BLOT

ORG 740  

Documentation

Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 2. Earlier versions and additional languages can be found in the document archive.

Anti-Tissue-Transglutaminase IgG

Anti-Tissue-Transglutaminase IgG is an ELISA test for the quantitative determination of IgG antibodies against tissue transglutaminase (tTG) in human serum or plasma.

Specifications

Product Number ORG 240G
Tests24 Alegria® strips
Calibrationinternal
Calculationquantitative
Range0 - 200 U/ml
Cut-off10 U/ml
Coating tissue transglutaminase (tTG) (human recombinant)
ELISA

ORG 540A   ORG 540G   ORG 540S  

BLOT

ORG 740  

Documentation

Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 2. Earlier versions and additional languages can be found in the document archive.

Anti-Tissue-Transglutaminase Screen

Anti-Tissue-Transglutaminase Screen is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG and IgA antibodies against tissue transglutaminase (tTG) in human serum or plasma.

Specifications

Product Number ORG 240S
Tests24 Alegria® strips
Calibrationinternal
Calculationquantitative
Range0 - 200 U/ml
Cut-off15 U/ml
Coating tissue transglutaminase (tTG) (human recombinant)
ELISA

ORG 540A   ORG 540G   ORG 540S  

BLOT

ORG 740  

Documentation

Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 2. Earlier versions and additional languages can be found in the document archive.
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