ANAscreen
ANAscreen is an ELISA test system for the qualitative measurement of IgG antibodies against nuclear antigens, SS-A 52, SS-A 60, SS-B, RNP-70, Sm, RNP/Sm, Scl-70, Centromere B, and Jo-1, in human serum or plasma.
Antinuclear antibodies (ANA) are detected in patients with systemic autoimmune diseases such as systemic lupus erythematosus (SLE), Sjögren’s syndrome, Sharp syndrome, polymyositis/dermatomyositis, and progressive systemic scleroderma (PSS) with CREST syndrome. ANA thus partially act as makers for the individual connective tissue diseases. Each individual well of the ANAscreen test is coated with a mixture of nine human recombinant and native, highly purified antigens, allowing for sensitive detection of these autoantibodies. After a positive result with this test, further differentiation of the autoantibodies should be carried out with the ANAcombi test or the respective single antigen ELISA assays from ORGENTEC.
Specifications
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Instruction for Use Revision 4. Earlier versions and additional languages can be found in the document archive. |