Anti-Insulin
Anti-Insulin is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against animal (beef, pork) and human insulin in human serum or plasma.
Anti-Insulin is an ELISA test for the quantitative determination of IgG antibodies against human, bovine and pig insulin in human serum or plasma.
Type I diabetes mellitus is an autoimmune disease triggered by autoantibodies against pancreatic islet cells and against insulin itself. Autoantibodies against insulin can appear in the prediabetic phase of type I diabetes mellitus or once the condition manifests. These autoantibodies are found in 50 to 70 % of children with diabetes mellitus and 20 to 30 % of affected adults.
In rare cases, insulin-dependent diabetes patients generate antibodies against exogenous insulin. These antibodies can give rise to insulin-resistance and should therefore be controlled regularly when monitoring insulin therapy.
The wells of the Anti-Insulin ELISA from ORGENTEC are coated with a mixture of bovine, pig, and recombinant human insulin.
Specifications
Product Number |
ORG 220 |
Tests | 24 Alegria® strips |
Calibration | internal |
Calculation | quantitative |
Range | 0 - 100 U/ml |
Cut-off | 10 U/ml |
Coating |
insulin (bovine, porcine, human recombinant) |
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Instruction for Use Revision 5. Earlier versions and additional languages can be found in the document archive.
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