Anti-Jo-1 is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against Jo-1 in human serum or plasma.

Autoantibodies against the Jo-1 antigen (histidyl-tRNA synthetase), which is one of the extractable nuclear antigens (ENA), are an accepted, highly specific marker for idiopathic myositis. The diagnostic sensitivity of Anti-Jo-1 detection for idiopathic myositis in adults is as high 30 %, for polymyositis it is up to 46 %. In cases of juvenile myositis, on the other hand, antibodies against Jo-1 are rare. Their diagnostic specificity for autoimmune myositis is nearly 100 %. Anti-Jo-1 antibodies are absent in cases of neuromuscular disease without myositis.


Product Number ORG 213
Tests24 Alegria® strips
Range0 - 200 U/ml
Cut-off25 U/ml
Coating histidyl-tRNA synthetase (Jo-1)

ORG 200   ORG 206   ORG 238  


ORG 506   ORG 513   ORG 514   ORG 538   ORG 539   ORG 600  


Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 4. Earlier versions and additional languages can be found in the document archive.

We use cookies on our website. Some of them are essential for the operation of the site, while others help us to improve this site and the user experience (tracking cookies). You can decide for yourself whether you want to allow cookies or not. Please note that if you reject them, you may not be able to use all the functionalities of the site.