Anti-beta-2-Glycoprotein
The assay contributes to the diagnosis of antiphospholipid syndrome (APS).
The clinical symptoms of APS alone are not sufficiently specific to make a definitive diagnosis. Laboratory tests thus play an important role in the diagnosis of the disease. In patients with APS, autoantibodies are formed that bind to phospholipids like cardiolipin or to phospholipid-binding proteins like beta-2-glycoprotein. Detection of these autoantibodies is an integral part of the classification criteria issued by the International Society on Thrombosis and Hemostasis.
Beta-2-GPI antibodies are associated with the occurrence of arterial or venous thrombosis, as well as with recurring miscarriage. Beta-2-GPI antibodies are considered to have a higher specificity than cardiolipin antibodies for the detection of APS; they can be detected even when the cardiolipin test result is negative.
Anti-beta-2-Glycoprotein I IgA
Anti-beta-2-Glycoprotein I IgA is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgA antibodies against beta-2-glycoprotein I in human serum or plasma.
Specifications
| Product Number |
ORG 221A |
| Tests | 24 Alegria® strips |
| Calibration | Harris sera, IRP 97/656 (IgG), HCAL (IgG) / EY2C9 (IgM) |
| Calculation | quantitative |
| Range | 0 - 100 U/ml |
| Cut-off | 8 U/ml |
| Coating |
beta-2-glycoprotein I (beta-2-GPI) |
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Instruction for Use Revision 5. Earlier versions and additional languages can be found in the document archive.
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Anti-beta-2-Glycoprotein I IgG
Anti-beta-2-Glycoprotein I IgG is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against beta-2-glycoprotein I in human serum or plasma.
Specifications
| Product Number |
ORG 221G |
| Tests | 24 Alegria® strips |
| Calibration | Harris sera, IRP 97/656 (IgG), HCAL (IgG) / EY2C9 (IgM) |
| Calculation | quantitative |
| Range | 0 - 100 U/ml |
| Cut-off | 8 U/ml |
| Coating |
beta-2-glycoprotein I (beta-2-GPI) |
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Instruction for Use Revision 5. Earlier versions and additional languages can be found in the document archive.
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Anti-beta-2-Glycoprotein I IgM
Anti-beta-2-Glycoprotein I IgM is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgM antibodies against beta-2-glycoprotein I in human serum or plasma.
Specifications
| Product Number |
ORG 221M |
| Tests | 24 Alegria® strips |
| Calibration | Harris sera, IRP 97/656 (IgG), HCAL (IgG) / EY2C9 (IgM) |
| Calculation | quantitative |
| Range | 0 - 100 U/ml |
| Cut-off | 8 U/ml |
| Coating |
beta-2-glycoprotein I (beta-2-GPI) |
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Instruction for Use Revision 5. Earlier versions and additional languages can be found in the document archive.
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Anti-beta-2-Glycoprotein I Screen
Anti-beta-2-Glycoprotein I Screen is an ELISA-based, automated, in-vitro test system for the quantitative determination of antibodies against beta-2-glycoprotein I in human serum or plasma. This test simultaneously tests for IgA, IgM, and IgG antibodies.
Specifications
| Product Number |
ORG 221S |
| Tests | 24 Alegria® strips |
| Calibration | Harris sera, IRP 97/656 (IgG), HCAL (IgG) / EY2C9 (IgM) |
| Calculation | quantitative |
| Range | 0 - 90 U/ml |
| Cut-off | 10 U/ml |
| Coating |
beta-2-glycoprotein I (beta-2-GPI) |
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Instruction for Use Revision 7. Earlier versions and additional languages can be found in the document archive.
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