Anti-Tissue-Transglutaminase
The Anti- Tissue-Transglutaminase ELISA tests from ORGENTEC are used for automated quantitative determination of IgA and/or IgG antibodies against Tissue-Transglutaminase (tTG) in human serum or plasma. The assays Anti-Tissue-Transglutaminase IgA, Anti-Tissue-Transglutaminase IgG, and Anti-Tissue-Transglutaminase Screen support a diagnosis of celiac disease.
Celiac disease (sprue) is one of the most common food-induced diseases. It manifests itself as hypersensitivity to gluten in food, which is found in wheat, rye, and barley.
tTG belongs to a family of calcium-dependent enzymes that catalyze the transfer of protein-bound glutamine residues to primary amines. The enzyme is released by inflamed cells and is the primary antigen for autoantibodies of celiac disease patients.
The Anti-Tissue-Transglutaminase assay provides a simple, non-invasive alternative to conventional immunofluorescence. Its high reliability, sensitivity, and specificity make it an ideal tool for screening patients with clinical symptoms. The Anti-tTG test by ORGENTEC is available both for screening by simultaneous detection of IgG and IgA or as single tests for individual analysis of IgA or IgG antibodies.
Anti-Tissue-Transglutaminase IgA
Anti-Tissue-Transglutaminase IgA is an ELISA test for the quantitative determination of IgA antibodies against tissue transglutaminase (tTG) in human serum or plasma.
Specifications
| Product Number |
ORG 540A |
| Tests | 12 x 8 tests |
| Calibration | internal |
| Calculation | quantitative |
| Range | 0 - 200 U/ml |
| Cut-off | 10 U/ml |
| Coating |
tissue transglutaminase (tTG) (human recombinant) |
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Instruction for Use Revision 4. Earlier versions and additional languages can be found in the document archive.
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Anti-Tissue-Transglutaminase IgG
Anti-Tissue-Transglutaminase IgG is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against tissue transglutaminase (tTG) in human serum or plasma.
Specifications
| Product Number |
ORG 540G |
| Tests | 12 x 8 tests |
| Calibration | internal |
| Calculation | quantitative |
| Range | 0 - 200 U/ml |
| Cut-off | 10 U/ml |
| Coating |
tissue transglutaminase (tTG) (human recombinant) |
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|
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Instruction for Use Revision 4. Earlier versions and additional languages can be found in the document archive.
|
Anti-Tissue-Transglutaminase Screen
Anti-Tissue-Transglutaminase Screen is an ELISA test for the quantitative determination of IgG and IgA antibodies against tissue transglutaminase (tTG) in human serum or plasma.
Specifications
| Product Number |
ORG 540S |
| Tests | 12 x 8 tests |
| Calibration | internal |
| Calculation | quantitative |
| Range | 0 - 200 U/ml |
| Cut-off | 15 U/ml |
| Coating |
tissue transglutaminase (tTG) (human recombinant) |
|
|
|
Instruction for Use Revision 3. Earlier versions and additional languages can be found in the document archive.
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