Anti-dsDNA IgG

Anti-dsDNA IgG is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against double-stranded DNA in human serum or plasma.

This assay is used for initial diagnosis in cases of systemic lupus erythematosus and for differential diagnosis of systemic autoimmune diseases for which high titres of antibodies against antinuclear antibodies (ANA) are found. Autoantibodies against DNA and histones bind to single-stranded (ssDNA) and double-stranded (dsDNA). Antibodies against dsDNA are predominantly detected during the active stages of the disease and serve as activity markers for SLE. They are a prognostic indicator of severe, multisystemic disease progression.

Specifications

Product Number ORG 204G
Tests24 Alegria® strips
CalibrationWHO Wo/80
Calculationquantitative
Range0 - 200 IU/ml
Cut-off20 IU/ml
Coating dsDNA
Alegria

ORG 200  

ELISA

ORG 600   ORG 604  

Documentation

Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 6. Earlier versions and additional languages can be found in the document archive.

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