Anti-SS-A 52
Anti-SS-A 52 is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against SS-A 52 in human serum or plasma.
This test is used for the differential diagnosis and monitoring of systemic rheumatic inflammatory autoimmune diseases.
Autoantibodies against SS-A 52 are primarily found in patients with collagenoses, especially those with Sjögren’s syndrome and various forms of Lupus erythematosus. Autoantibodies against the SS-A 52 proteins are specific to Sjögren’s syndrome, though they are less specific than SS-A 60 antibodies. In cases of myositis, anti-SS-A 52 are found together with other myositis-specific antibodies such as Anti-SRP, Anti-PM-SCl, or antibodies against aminoacyl-tRNA synthetase. In these patients, there is no connection to Sjögren’s syndrome.
Specifications
Product Number |
ORG 252 |
Tests | 24 Alegria® strips |
Calibration | internal |
Calculation | quantitative |
Range | 0 - 200 U/ml |
Cut-off | 25 U/ml |
Coating |
SS-A 52 (Ro 52) |
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Instruction for Use Revision 5. Earlier versions and additional languages can be found in the document archive.
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