Rheumatoid Factor
Rheumatoid Factors are the best-known diagnostic markers for rheumatoid arthritis (RA), and presence of rheumatoid factors is an integral part of the current ACR criteria for classification of RA. Rheumatoid factors are a subcategory of immunoglobulins that specifically bind to the Fc regions of IgG.
Elevated concentrations of rheumatoid factors are often correlated with a more severe course of the disease. IgM RF may precede the onset of RA by several years. In established RA, high titer serum IgM RF indicate poor prognosis. The presence of either IgG or IgA RF in patients with long-standing RA may be a prognostic indicator of systemic manifestations.
For more extensive serological diagnosis, monitoring of treatment, and early diagnosis of rheumatoid arthritis, we recommend our Anti-MCV ELISA.
Rheumatoid Factor IgA
Rheumatoid Factor IgA is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgA rheumatoid factors (RF) in human serum or plasma.
Specifications
| Product Number |
ORG 222A |
| Tests | 24 Alegria® strips |
| Calibration | WHO 64/2 |
| Calculation | quantitative |
| Range | 0 - 500 U/ml |
| Cut-off | 20 U/ml |
| Coating |
Fc fragments of IgG (human) |
|
|
|
Instruction for Use Revision 6. Earlier versions and additional languages can be found in the document archive.
|
Rheumatoid Factor IgG
Rheumatoid Factor IgG is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG rheumatoid factors (RF) in human serum or plasma.
Specifications
| Product Number |
ORG 222G |
| Tests | 24 Alegria® strips |
| Calibration | WHO 64/2 |
| Calculation | quantitative |
| Range | 0 - 500 U/ml |
| Cut-off | 20 U/ml |
| Coating |
Fc fragments of IgG (human) |
|
|
|
Instruction for Use Revision 6. Earlier versions and additional languages can be found in the document archive.
|
Rheumatoid Factor IgM
Rheumatoid Factor IgM is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgM rheumatoid factors (RF) in human serum or plasma.
Specifications
| Product Number |
ORG 222M |
| Tests | 24 Alegria® strips |
| Calibration | WHO 64/2 |
| Calculation | quantitative |
| Range | 0 - 500 IU/ml |
| Cut-off | 20 IU/ml |
| Coating |
Fc fragments of IgG (human) |
|
|
|
Instruction for Use Revision 6. Earlier versions and additional languages can be found in the document archive.
|
