Anti-PR3 (cANCA)

Anti-PR3 is an ELISA test for the quantitative determination of IgG antibodies against proteinase 3 (PR3) in human serum or plasma.

The anti-PR3 assay is an important element in the diagnosis of granulomatosis with polyangiitis (Wegener’s granulomatosis). Antineutrophil cytoplasmic antibodies (ANCA) are a group of autoantibodies directed against the cytoplasmic components of the neutrophils and monocytes. Detection of ANCA is carried out by indirect immunofluorescence (IIF), followed by antigen-specific ELISA tests such as Anti-PR3 oder Anti-PR3 hs (high sensitive) ORG 618, ORG 318).

The Anti-PR3 (hs (high sensitive) has unusually high sensitivity (96 %) and simultaneously high specificity (99 %), providing outstanding diagnostic power in ANCA diagnosis. In addition, results from this test correlate excellently with those of indirect immunofluorescence tests.


Product Number ORG 518
Tests12 x 8 tests
Range0 - 100 U/ml
Cut-off5 U/ml
Coating proteinase 3

ORG 218  


Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 3. Earlier versions and additional languages can be found in the document archive.

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