Anti-Mycoplasma pneumoniae

Mycoplasma pneumoniae is one of the smallest free-living organisms. In addition to Chlamydia and Legionella, M. pneumoniae is one of the primary causes of community-acquired pneumonia.
The serological detection of pathogen-specific antibodies by ELISA is a commonly used method for diagnosing M. pneumoniae infections. Antibodies against M. pneumoniae adhesins are particularly useful because of their high sensitivity and specificity. Adhesins are special surface molecules that help the bacteria stick to the mucosa of the respiratory tract.
The individual detection of IgM, IgG, and IgA antibodies is used to differentiate between primary infections and reinfections. IgM antibodies usually appear seven to ten days after onset of the infection. They are often absent in cases of reinfection. IgG titers increase slowly as the disease progresses, usually reaching a maximum about five weeks after onset of clinical symptoms, after which they slowly decrease. A significant increase in IgG titer within two weeks confirms acute infection. High IgA titers are the best indicator of acute infection in adults; however, low titers of IgA antibodies can persist over longer periods of time.

Anti-Mycoplasma pneumoniae IgA

Alegria® Anti-Mycoplasma pneumoniae IgA for Alegria® is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgA antibodies against Mycoplasma pneumoniae in human serum or plasma.

Specifications

Product Number ORG 915A
Tests24 Alegria® strips
Calibrationinternal
Calculationquantitative
Range0 - 200 U/ml
Cut-off25 U/ml
Coating immunoglobulin class specific natural and recombinant proteins

Documentation

Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 3. Earlier versions and additional languages can be found in the document archive.

Anti-Mycoplasma pneumoniae IgG

Alegria® Anti-Mycoplasma pneumoniae IgG is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies againstMycoplasma pneumoniae in human serum or plasma.

Specifications

Product Number ORG 915G
Tests24 Alegria® strips
Calibrationinternal
Calculationquantitative
Range0 - 200 U/ml
Cut-off25 U/ml
Coating immunoglobulin class specific natural and recombinant proteins

Documentation

Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 3. Earlier versions and additional languages can be found in the document archive.

Anti-Mycoplasma pneumoniae IgM Abs.

Anti-Mycoplasma pneumoniae IgM for Alegria® is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgM antibodies against Mycoplasma pneumoniae in human serum or plasma.
The Anti-Mycoplasma pneumoniae IgM Abs. (ORG 915MX) test is equipped with the ORGENTEC rheumatoid factor absorbent. This reagent absorbs any rheumatoid factors that may be present during sample processing in the Alegria® instrument, making separate preparation of the serum sample unnecessary.

Specifications

Product Number ORG 915MX
Tests24 Alegria® strips
Calibrationinternal
Calculationquantitative
Range0 - 200 U/ml
Cut-off25 U/ml
Coating immunoglobulin class specific natural and recombinant proteins

Documentation

Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 3. Earlier versions and additional languages can be found in the document archive.

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