Anti-Rib-P

Anti-Rib-P is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against ribosomal P proteins in human serum or plasma. They recognize a common epitope of the three phosphoproteins P0, P1 and P2 of the 60S subunit of the ribosomal complex.

Like anti-nuclear antibodies (ANA), anti-cytoplasmic antibodies play a role in rheumatic disease. Of these, the anti-ribosomal antibodies (ARA) are the best characterized. Autoantibodies against ribosomal P-proteins are highly specific markers for diagnostics of systemic lupus erythematosus, because they rarely occur in other autoimmune diseases. ARA are found in only about 10 % of randomly selected SLE patients, but are detected in up to 40 % of SLE patients whose disease status is active. Anti-Rib-P detection is recommended in cases of suspected SLE when antibodies against Sm antigens and double-stranded DNA are absent. Use of the Anti-Rib-P ELISA from ORGENTEC is also indicated when lupus-induced psychosis is suspected.

Specifications

Product Number ORG 217
Tests24 Alegria® strips
CalibrationCDC sera
Calculationquantitative
Range0 - 200 U/ml
Cut-off 10 U/ml
Coating ribosomal P protein (Rib-P)
ELISA

ORG 517  

BLOT

ORG 710   ORG 760  

Documentation

Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 4. Earlier versions and additional languages can be found in the document archive.
Cookies make it easier for us to provide you with our services. With the usage of our services you permit us to use cookies.
More information Ok