Anti-HSV-2 IgM Abs.

Anti-HSV-2 IgM with rheumatoid factor absorbent is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgM antibodies against herpes simplex virus type 2 (HSV-2) in human serum or plasma.
IgM-class rheumatoid factor antibodies can distort the results of pathogen-specific IgM antibody tests. The Anti-HSV-1 IgM Abs. test is equipped with the ORGENTEC rheumatoid factor absorbent. This reagent absorbs any rheumatoid factors that may be present during sample processing in the Alegria® instrument, making separate preparation of the serum sample unnecessary.

The human pathogenic type 1 and 2 herpes simplex viruses (HSV-1 and HSV-2) infect epithelial cells of the mucous membranes: HSV-1 primarily in the head area (herpes labialis), HSV-2 in the genital and anal areas (herpes genitalis). In the acute stage, the infection causes formation of characteristic blisters. In transitioning to the latent stage, these viruses enter the sensory nerves and spinal ganglia, where they persist throughout the lifetime of the patient. They are often reactivated, causing a recurrence of symptoms. It is always recommended to determine a woman’s HSV status during pregnancy to estimate the newborn’s risk for perinatal infection. Detection of IgM antibodies against HSV virus is important to confirm an acute primary infection, which has been detected via PCR. Besides, IgM antibodies may also be detectable in cases of recurrent or persistent infection. IgG antibodies against the type-specific glycoprotein G1 are formed two to three months after a primary infection with the type 1 herpes simplex virus. IgG-class antibodies against glycoprotein G2 are detectable several weeks after primary infection.


Product Number ORG 904MX
Tests24 Alegria® strips
Range0 - 200 U/ml
Cut-off25 U/ml
Coating HSV-2 whole-virus antigen

ORG 905G   ORG 905MX   ORG 905GL  


Instruction for Use
Safety Data Sheet

Document Archive
Instruction for Use Revision 4. Earlier versions and additional languages can be found in the document archive.

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